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Πλοήγηση ανά Θέμα "genetic risk"

Αποτελέσματα 1-20 από 53

    • The -938C>A polymorphism in MYD88 is associated with susceptibility to tuberculosis: A pilot study 

      Aggelou K., Siapati E.K., Gerogianni I., Daniil Z., Gourgoulianis K., Ntanos I., Simantirakis E., Zintzaras E., Mollaki V., Vassilopoulos G. (2016)
      Introduction. Tuberculosis (TB) is a major disease worldwide, caused by Mycobacterium tuberculosis (MTB) infection.The Toll- Like Receptor (TLR) pathway plays a crucial role in the recognition of MTB. Aim. The present study ...

    • ADORA2A rS5760423 and CYP1A2 rs762551 polymorphisms as risk factors for parkinson’s disease 

      Siokas V., Aloizou A.-M., Tsouris Z., Liampas I., Liakos P., Calina D., Docea A.O., Tsatsakis A., Bogdanos D.P., Hadjigeorgiou G.M., Dardiotis E. (2021)
      Background: Parkinson’s disease (PD) is the second commonest neurodegenerative disease. The genetic basis of PD is indisputable. Both ADORA2A rs5760423 and CYP1A2 rs762551 have been linked to PD, to some extent, but the ...

    • Apolipoprotein E Polymorphism and Left Ventricular Failure in Beta-Thalassemia: A Multivariate Meta-Analysis 

      Dimou N.L., Pantavou K.G., Bagos P.G. (2017)
      Apolipoprotein E (ApoE) is potentially a genetic risk factor for the development of left ventricular failure (LVF), the main cause of death in beta-thalassemia homozygotes. In the present study, we synthesize the results ...

    • Apolipoprotein E4 and meningeal lymphatics in Alzheimer disease: a conceptual framework 

      Mentis A.-F.A., Dardiotis E., Chrousos G.P. (2021)
      The potential existence and roles of the meningeal lymphatic system in normal and pathological brain function have been a long-standing enigma. Recent evidence suggests that meningeal lymphatic vessels are present in both ...

    • AQP4 tag SNPs in patients with intracerebral hemorrhage in Greek and Polish population 

      Dardiotis E., Siokas V., Marogianni C., Aloizou A.-M., Sokratous M., Paterakis K., Dardioti M., Grigoriadis S., Brotis A., Kapsalaki E., Fountas K., Jagiella J., Hadjigeorgiou G.M. (2019)
      Backround: A relatively small number of genetic variants are implicated to pathophysiology of intracerebral hemorrhage (ICH). Aquaporin-4 (AQP4) has been reported to be implicated in the pathophysiological processes of ICH ...

    • Assessment of TREM2 rs75932628 variant’s association with Parkinson’s disease in a Greek population and Meta-analysis of current data 

      Dardiotis E., Rikos D., Siokas V., Aloizou A.-M., Tsouris Z., Sakalakis E., Brotis A.G., Bogdanos D.P., Hadjigeorgiou G.M. (2021)
      Background: Α number of genetic variants are considered to confer susceptibility to Parkinson’s disease (PD). Rs75392628 (R47H), a rare variant of TREM2 gene, has been linked to PD, although its role on PD remains conflicting. ...

    • Association of p16 (CDKN2A) polymorphisms with the development of HPV16-related precancerous lesions and cervical cancer in the Greek population 

      Tsakogiannis D., Moschonas G.D., Bella E., Kyriakopoulou Z., Amoutzias G.D., Dimitriou T.G., Kottaridi C., Markoulatos P. (2018)
      The tumor suppressor protein p16 plays a fundamental role in cell cycle regulation and exerts a protective effect against tumor growth. Two different polymorphisms at positions 540 and 580 at the 3′UTR of exon 3 of p16 ...

    • A case-control study on the risk factors for meningococcal disease among children in Greece 

      Hadjichristodoulou C., Mpalaouras G., Vasilopoulou V., Katsioulis A., Rachiotis G., Theodoridou K., Tzanakaki G., Syriopoulou V., Theodoridou M. (2016)
      Purpose: The aim of this study was to identify environmental or genetic risk factors that are associated with invasive meningococcal disease (IMD) in children in Greece. Methods: A case-control study was performed in 133 ...

    • Chondrocyte protein co-synthesis network analysis links ECM mechanosensing to metabolic adaptation in osteoarthritis 

      Destouni A., Tsolis K.C., Economou A., Papathanasiou I., Balis C., Mourmoura E., Tsezou A. (2021)
      Background: Knee osteoarthritis (OA) is one of the most common structural OA disorders globally. Incomplete understanding of the fundamental biological aspects of osteoarthritis underlies the current lack of effective ...

    • Clinically meaningful parameters of progression and long-term outcome of Parkinson disease: AN international consensus statement 

      Puschmann, A.; Brighina, L.; Markopoulou, K.; Aasly, J.; Chung, S. J.; Frigerio, R.; Hadjigeorgiou, G.; Kõks, S.; Krüger, R.; Siuda, J.; Wider, C.; Zesiewicz, T. A.; Maraganore, D. M. (2015)
      Parkinson disease (PD) is associated with a clinical course of variable duration, severity, and a combination of motor and non-motor features. Recent PD research has focused primarily on etiology rather than clinical ...

    • Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores 

      de Rojas I., Moreno-Grau S., Tesi N., Grenier-Boley B., Andrade V., Jansen I.E., Pedersen N.L., Stringa N., Zettergren A., Hernández I., Montrreal L., Antúnez C., Antonell A., Tankard R.M., Bis J.C., Sims R., Bellenguez C., Quintela I., González-Perez A., Calero M., Franco-Macías E., Macías J., Blesa R., Cervera-Carles L., Menéndez-González M., Frank-García A., Royo J.L., Moreno F., Huerto Vilas R., Baquero M., Diez-Fairen M., Lage C., García-Madrona S., García-González P., Alarcón-Martín E., Valero S., Sotolongo-Grau O., Ullgren A., Naj A.C., Lemstra A.W., Benaque A., Pérez-Cordón A., Benussi A., Rábano A., Padovani A., Squassina A., de Mendonça A., Arias Pastor A., Kok A.A.L., Meggy A., Pastor A.B., Espinosa A., Corma-Gómez A., Martín Montes A., Sanabria Á., DeStefano A.L., Schneider A., Haapasalo A., Kinhult Ståhlbom A., Tybjærg-Hansen A., Hartmann A.M., Spottke A., Corbatón-Anchuelo A., Rongve A., Borroni B., Arosio B., Nacmias B., Nordestgaard B.G., Kunkle B.W., Charbonnier C., Abdelnour C., Masullo C., Martínez Rodríguez C., Muñoz-Fernandez C., Dufouil C., Graff C., Ferreira C.B., Chillotti C., Reynolds C.A., Fenoglio C., Van Broeckhoven C., Clark C., Pisanu C., Satizabal C.L., Holmes C., Buiza-Rueda D., Aarsland D., Rujescu D., Alcolea D., Galimberti D., Wallon D., Seripa D., Grünblatt E., Dardiotis E., Düzel E., Scarpini E., Conti E., Rubino E., Gelpi E., Rodriguez-Rodriguez E., Duron E., Boerwinkle E., Ferri E., Tagliavini F., Küçükali F., Pasquier F., Sanchez-Garcia F., Mangialasche F., Jessen F., Nicolas G., Selbæk G., Ortega G., Chêne G., Hadjigeorgiou G., Rossi G., Spalletta G., Giaccone G., Grande G., Binetti G., Papenberg G., Hampel H., Bailly H., Zetterberg H., Soininen H., Karlsson I.K., Alvarez I., Appollonio I., Giegling I., Skoog I., Saltvedt I., Rainero I., Rosas Allende I., Hort J., Diehl-Schmid J., Van Dongen J., Vidal J.-S., Lehtisalo J., Wiltfang J., Thomassen J.Q., Kornhuber J., Haines J.L., Vogelgsang J., Pineda J.A., Fortea J., Popp J., Deckert J., Buerger K., Morgan K., Fließbach K., Sleegers K., Molina-Porcel L., Kilander L., Weinhold L., Farrer L.A., Wang L.-S., Kleineidam L., Farotti L., Parnetti L., Tremolizzo L., Hausner L., Benussi L., Froelich L., Ikram M.A., Deniz-Naranjo M.C., Tsolaki M., Rosende-Roca M., Löwenmark M., Hulsman M., Spallazzi M., Pericak-Vance M.A., Esiri M., Bernal Sánchez-Arjona M., Dalmasso M.C., Martínez-Larrad M.T., Arcaro M., Nöthen M.M., Fernández-Fuertes M., Dichgans M., Ingelsson M., Herrmann M.J., Scherer M., Vyhnalek M., Kosmidis M.H., Yannakoulia M., Schmid M., Ewers M., Heneka M.T., Wagner M., Scamosci M., Kivipelto M., Hiltunen M., Zulaica M., Alegret M., Fornage M., Roberto N., van Schoor N.M., Seidu N.M., Banaj N., Armstrong N.J., Scarmeas N., Scherbaum N., Goldhardt O., Hanon O., Peters O., Skrobot O.A., Quenez O., Lerch O., Bossù P., Caffarra P., Dionigi Rossi P., Sakka P., Hoffmann P., Holmans P.A., Fischer P., Riederer P., Yang Q., Marshall R., Kalaria R.N., Mayeux R., Vandenberghe R., Cecchetti R., Ghidoni R., Frikke-Schmidt R., Sorbi S., Hägg S., Engelborghs S., Helisalmi S., Botne Sando S., Kern S., Archetti S., Boschi S., Fostinelli S., Gil S., Mendoza S., Mead S., Ciccone S., Djurovic S., Heilmann-Heimbach S., Riedel-Heller S., Kuulasmaa T., del Ser T., Lebouvier T., Polak T., Ngandu T., Grimmer T., Bessi V., Escott-Price V., Giedraitis V., Deramecourt V., Maier W., Jian X., Pijnenburg Y.A.L., Smith A.D., Saenz A., Bizzarro A., Lauria A., Vacca A., Solomon A., Anastasiou A., Richardson A., Boland A., Koivisto A., Daniele A., Greco A., Marianthi A., McGuinness B., Fin B., Ferrari C., Custodero C., Ferrarese C., Ingino C., Mangone C., Reyes Toso C., Martínez C., Cuesta C., Muchnik C., Joachim C., Ortiz C., Besse C., Johansson C., Zoia C.P., Laske C., Anastasiou C., Palacio D.L., Politis D.G., Janowitz D., Craig D., Mann D.M., Neary D., Jürgen D., Daian D., Belezhanska D., Kohler E., Castaño E.M., Koutsouraki E., Chipi E., De Roeck E., Costantini E., Vardy E.R.L.C., Piras F., Roveta F., Piras F., Prestia F.A., Assogna F., Salani F., Sala G., Lacidogna G., Novack G., Wilcock G., Thonberg H., Kölsch H., Weber H., Boecker H., Etchepareborda I., Piaceri I., Tuomilehto J., Lindström J., Laczo J., Johnston J., Deleuze J.-F., Harris J., Schott J.M., Priller J., Bacha J.I., Snowden J., Lisso J., Mihova K.Y., Traykov L., Morelli L., Brusco L.I., Rainer M., Takalo M., Bjerke M., Del Zompo M., Serpente M., Sanchez Abalos M., Rios M., Peltonen M., Herrman M.J., Kosmidis M.H., Kohler M., Rojo M., Jones M., Orsini M., Medel N., Olivar N., Fox N.C., Salvadori N., Hooper N.M., Galeano P., Solis P., Bastiani P., Mecocci P., Passmore P., Heun R., Antikainen R., Olaso R., Perneczky R., Germani S., López-García S., Love S., Mehrabian S., Bagnoli S., Kochen S., Andreoni S., Teipel S., Todd S., Pickering-Brown S., Natunen T., Tegos T., Laatikainen T., Strandberg T., Polvikoski T.M., Matoska V., Ciullo V., Cores V., Solfrizzi V., Lisetti V., Sevillano Z., Abdelnour C., Aguilera N., Alarcon E., Alegret M., Benaque A., Boada M., Buendia M., Cañabate P., Carracedo A., Corbatón-Anchuelo A., Diego S., Espinosa A., Gailhajenet A., Gil S., Guitart M., Hernández I., Ibarria M., Lafuente A., Macias J., Maroñas O., Martín E., Martínez M.T., Marquié M., Mauleón A., Montrreal L., Moreno-Grau S., Moreno M., Orellana A., Ortega G., Pancho A., Pelejá E., Pérez-Cordon A., Preckler S., Quintela I., Real L.M., Rosende-Roca M., Ruiz A., Sáez M.E., Sanabria A., Serrano-Rios M., Sotolongo-Grau O., Tárraga L., Valero S., Vargas L., Adarmes-Gómez A.D., Alarcón-Martín E., Alonso M.D., Álvarez I., Álvarez V., Amer-Ferrer G., Antequera M., Antúnez C., Baquero M., Bernal M., Blesa R., Boada M., Buiza-Rueda D., Bullido M.J., Burguera J.A., Calero M., Carrillo F., Carrión-Claro M., Casajeros M.J., Clarimón J., Cruz-Gamero J.M., de Pancorbo M.M., del Ser T., Diez-Fairen M., Escuela R., Garrote-Espina L., Fortea J., Franco-Macías E., Frank-García A., García-Alberca J.M., Garcia Madrona S., Garcia-Ribas G., Gómez-Garre P., Hernández I., Hevilla S., Jesús S., Labrador Espinosa M.A., Lage C., Legaz A., Lleó A., Lopez de Munain A., López-García S., Macias-García D., Manzanares S., Marín M., Marín-Muñoz J., Marín T., Marquié M., Martín Montes A., Martínez B., Martínez C., Martínez V., Martínez-Lage Álvarez P., Medina M., Mendioroz Iriarte M., Mir P., Molinuevo J.L., Pastor P., Pérez-Tur J., Periñán-Tocino T., Pineda-Sanchez R., Piñol-Ripoll G., Rábano A., Real de Asúa D., Rodrigo S., Rodríguez-Rodríguez E., Royo J.L., Ruiz A., Sanchez del Valle Díaz R., Sánchez-Juan P., Sastre I., Valero S., Vicente M.P., Vigo-Ortega R., Vivancos L., Macleod C., McCracken C., Brayne C., Bresner C., Grozeva D., Bellou E., Sommerville E.W., Matthews F., Leonenko G., Menzies G., Windle G., Harwood J., Phillips J., Bennett K., Luckuck L., Clare L., Woods R., Saad S., Burholt V., Jansen I.E., Rongve A., Kehoe P.G., Garcia-Ribas G., Sánchez-Juan P., Pastor P., Lopez de Munain A., García-Alberca J.M., Bullido M.J., Álvarez V., Real L.M., Scheltens P., Holstege H., Marquié M., Sáez M.E., Amouyel P., Schellenberg G.D., Williams J., Seshadri S., van Duijn C.M., Mather K.A., Sánchez-Valle R., Serrano-Ríos M., Orellana A., Tárraga L., Blennow K., Huisman M., Andreassen O.A., Posthuma D., Clarimón J., Boada M., van der Flier W.M., Ramirez A., Lambert J.-C., van der Lee S.J., Ruiz A., EADB contributors, The GR@ACE study group, DEGESCO consortium, IGAP (ADGC, CHARGE, EADI, GERAD), PGC-ALZ consortia (2021)
      Genetic discoveries of Alzheimer’s disease are the drivers of our understanding, and together with polygenetic risk stratification can contribute towards planning of feasible and efficient preventive and curative clinical ...

    • Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach 

      Silveira, A. C.; Morrison, M. A.; Ji, F.; Xu, H.; Reinecke, J. B.; Adams, S. M.; Arneberg, T. M.; Janssian, M.; Lee, J. E.; Yuan, Y.; Schaumberg, D. A.; Kotoula, M. G.; Tsironi, E. E.; Tsiloulis, A. N.; Chatzoulis, D. Z.; Miller, J. W.; Kim, I. K.; Hageman, G. S.; Farrer, L. A.; Haider, N. B.; DeAngelis, M. M. (2010)
      To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). ...

    • Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations 

      Boer C.G., Hatzikotoulas K., Southam L., Stefánsdóttir L., Zhang Y., Coutinho de Almeida R., Wu T.T., Zheng J., Hartley A., Teder-Laving M., Skogholt A.H., Terao C., Zengini E., Alexiadis G., Barysenka A., Bjornsdottir G., Gabrielsen M.E., Gilly A., Ingvarsson T., Johnsen M.B., Jonsson H., Kloppenburg M., Luetge A., Lund S.H., Mägi R., Mangino M., Nelissen R.R.G.H.H., Shivakumar M., Steinberg J., Takuwa H., Thomas L.F., Tuerlings M., Loughlin J., Arden N., Birrell F., Carr A., Deloukas P., Doherty M., McCaskie A.W., Ollier W.E.R., Rai A., Ralston S.H., Spector T.D., Wallis G.A., Martinsen A.E., Willer C., Fors E.A., Mundal I., Hagen K., Nilsen K.B., Lie M.U., Børte S., Brumpton B., Nielsen J.B., Fritsche L.G., Zhou W., Heuch I., Storheim K., Tyrpenou E., Koukakis A., Chytas D., Evangelopoulos D.S., Efstathios C., Pneumaticos S., Nikolaou V.S., Malizos K., Anastasopoulou L., Abecasis G., Baras A., Cantor M., Coppola G., Deubler A., Economides A., Lotta L.A., Overton J.D., Reid J.G., Shuldiner A., Karalis K., Siminovitch K., Beechert C., Forsythe C., Fuller E.D., Gu Z., Lattari M., Lopez A., Schleicher T.D., Padilla M.S., Widom L., Wolf S.E., Pradhan M., Manoochehri K., Bai X., Balasubramanian S., Boutkov B., Eom G., Habegger L., Hawes A., Krasheninina O., Lanche R., Mansfield A.J., Maxwell E.K., Nafde M., O'Keeffe S., Orelus M., Panea R., Polanco T., Rasool A., Salerno W., Staples J.C., Li D., Sharma D., Banerjee I., Bovijn J., Locke A., Verweij N., Haas M., Hindy G., De T., Akbari P., Sosina O., Ferreira M.A.R., Jones M.B., Mighty J., LeBlanc M.G., Mitnaul L.J., Babis G.C., Cheung J.P.Y., Kang J.H., Kraft P., Lietman S.A., Samartzis D., Slagboom P.E., Stefansson K., Thorsteinsdottir U., Tobias J.H., Uitterlinden A.G., Winsvold B., Zwart J.-A., Davey Smith G., Sham P.C., Thorleifsson G., Gaunt T.R., Morris A.P., Valdes A.M., Tsezou A., Cheah K.S.E., Ikegawa S., Hveem K., Esko T., Wilkinson J.M., Meulenbelt I., Lee M.T.M., van Meurs J.B.J., Styrkársdóttir U., Zeggini E., arcOGEN Consortium, HUNT All-In Pain, ARGO Consortium, Regeneron Genetics Center (2021)
      Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated ...

    • Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis 

      Liu, J. Z.; Hov, J. R.; Folseraas, T.; Ellinghaus, E.; Rushbrook, S. M.; Doncheva, N. T.; Andreassen, O. A.; Weersma, R. K.; Weismüller, T. J.; Eksteen, B.; Invernizzi, P.; Hirschfield, G. M.; Gotthardt, D. N.; Pares, A.; Ellinghaus, D.; Shah, T.; Juran, B. D.; Milkiewicz, P.; Rust, C.; Schramm, C.; Muler, T.; Srivastava, B.; Dalekos, G.; Nöthen, M. M.; Herms, S.; Winkelmann, J.; Mitrovic, M.; Braun, F.; Ponsioen, C. Y.; Croucher, P. J. P.; Sterneck, M.; Teufel, A.; Andrew, L. Mason; Saarela, J.; Leppa, V.; Dorfman, R.; Alvaro, D.; Floreani, A.; Onengut-Gumuscu, S.; Rich, S. S.; Thompson, W. K.; Schork, A. J.; Næss, S.; Thomsen, I.; Mayr, G.; König, I. R.; Hveem, K.; Cleynen, I.; Gutierrez-Achury, J.; Ricaño-Ponce, I.; Van Heel, D.; Björnsson, E.; Sandford, R. N.; Durie, P. R.; Melum, E.; Vatn, M. H.; Silverberg, M. S.; Duerr, R. H.; Padyukov, L.; Brand, S.; Sans, M.; Annese, V.; Achkar, J. P.; Boberg, K. M.; Marschall, H. U.; Chazouillères, O.; Bowlus, C. L.; Wijmenga, C.; Schrumpf, E.; Vermeire, S.; Albrecht, M.; Rioux, J. D.; Alexander, G.; Bergquist, A.; Cho, J.; Schreiber, S.; Manns, M. P.; Färkkilä, M.; Dale, A. M.; Chapman, R. W.; Konstantinos, N. Lazaridis; Franke, A.; Anderson, C. A.; Karlsen, T. H. (2013)
      Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation. We compared 3,789 PSC cases of ...

    • Dna repair gene polymorphisms and susceptibility to urothelial carcinoma in a southeastern european population 

      Samara M., Papathanassiou M., Mitrakas L., Koukoulis G., Vlachostergios P.J., Tzortzis V. (2021)
      Single nucleotide polymorphisms (SNPs) in DNA repair genes may predispose to urothelial carcinoma of the bladder (UCB). This study focused on three specific SNPs in a population with high exposure to environmental carcinogens ...

    • Does SCFD1 rs10139154 Polymorphism Decrease Alzheimer’s Disease Risk? 

      Stamati P., Siokas V., Aloizou A.-M., Karampinis E., Arseniou S., Rakitskii V.N., Tsatsakis A., Spandidos D.A., Gozes I., Mitsias P.D., Bogdanos D.P., Hadjigeorgiou G.M., Dardiotis E. (2019)
      Α number of genetic variants have been associated with Alzheimer’s disease (AD) susceptibility. Sec1 family domain-containing protein 1 (SCFD1) gene polymorphism rs10139154 has recently been implicated in the risk of ...

    • Efforts to create an artificial testis: Culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment 

      Soffikitis, N.; Pappas, E.; Kawatani, A.; Baltogiannis, D.; Loutradis, D.; Kanakas, N.; Giannakis, D.; Dimitriadis, F.; Tsoukanelis, K.; Georgiou, I.; Makrydimas, G.; Mio, Y.; Tarlatzis, V.; Melekos, M.; Miyagawa, I. (2005)
      Induction of meiotic and post-meiotic alterations of male germ cells in vitro has been the target of several research efforts since 1960. However, to date, the establishment of an ideal culture system in which spermatogonial ...

    • Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study 

      Wang L., Heckman M.G., Aasly J.O., Annesi G., Bozi M., Chung S.J., Clarke C., Crosiers D., Eckstein G., Garraux G., Hadjigeorgiou G.M., Hattori N., Jeon B., Kim Y.J., Kubo M., Lesage S., Lin J.J., Lynch T., Lichtner P., Mellick G.D., Mok V., Morrison K.E., Quattrone A., Satake W., Silburn P.A., Stefanis L., Stockton J.D., Tan E.K., Toda T., Brice A., Van Broeckhoven C., Uitti R.J., Wirdefeldt K., Wszolek Z., Xiromerisiou G., Maraganore D.M., Gasser T., Krüger R., Farrer M.J., Ross O.A., Sharma M. (2017)
      A recent study MacLeod et al. has shown that an interaction between variants at the LRRK2 and PARK16 loci influences risk of development of Parkinson's disease (PD). Our study examines the proposed interaction between LRRK2 ...

    • Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia 

      Hackinger S., Prins B., Mamakou V., Zengini E., Marouli E., Brčić L., Serafetinidis I., Lamnissou K., Kontaxakis V., Dedoussis G., Gonidakis F., Thanopoulou A., Tentolouris N., Tsezou A., Zeggini E. (2018)
      The epidemiologic link between schizophrenia (SCZ) and type 2 diabetes (T2D) remains poorly understood. Here, we investigate the presence and extent of a shared genetic background between SCZ and T2D using genome-wide ...

    • FcγRIIa-H131R variant is associated with inferior response in diffuse large B cell lymphoma: A meta-analysis of genetic risk 

      Ziakas P.D., Poulou L.S., Zintzaras E. (2016)
      Purpose: Low-affinity variants FcγRIIIa-V158F and FcγRI-Ia-H131R may alter response to rituximab-based chemotherapy in diffuse large B-cell lymphoma (DLBCL) but available clinical evidence is inconclusive. Our purpose was ...